Publications
Visit Alexander’s Google Scholar Profile for the most up-to-date list of publications.
Publications (First Author)
Vlahos A.E., Call C.C., Kadaba S.E., Guo S., Gao X.J. “Compact Programmable Control of Protein Secretion in Mammalian Cells.”
Available on BioRxiv: https://doi.org/10.1101/2023.10.04.560774
Vlahos A.E., Kang J., Aldrete C.A., Zhu R., Chong L.S., Elowitz M.B., Gao X.J. “Protease-controlled secretion and display of intercellular signals.” Nature Communications, 13, 912, 2022.
Press Release: “‘Protein circuits’ move a step closer to cell-to-cell communication”
Vlahos A.E., Talior-Volodarsky I., Kinney S.M., Sefton M.V. “A scalable device-less biomaterial approach for subcutaneous islet transplantation.” Biomaterials 269, 120499, 2021.
Vlahos A.E., Kinney S.M., Kingston B.R., Keshavjee S., Won S., Martyts A., Chan W.C.W., Sefton M.V. “Endothelialized collagen based pseudo-islets enables tuneable subcutaneous diabetes therapy.” Biomaterials 232, 119710, 2020.
Work highlighted as Editor’s Choice in Science Translational Medicine: “Organoid optimization: Engineering a better cell therapy to treat type 1 diabetes”
Press Release: “U of T researchers develop method to improve transplantation of artificial insulin-producing cells”
Vlahos A.E., Sefton M.V. “ Endothelialized collagen modules for islet tissue engineering.” Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas Volume 2, Chapter 20, 277-287, 2020.
Vlahos A.E., Sefton M.V. “Muted fibrosis from protected islets.” Nature Biomedical Engineering 2 (11), 791-792, 2018.
Vlahos A.E., Cober N., Sefton M.V. “Modular tissue engineering for the vascularization of subcutaneously transplanted pancreatic islets.” PNAS 114 (35), 9337-9342, 2017.
Press Release: “The best place to treat type 1 diabetes might be just under your skin”
Publications (Contributing Author)
Aldrete C.A., Vlahos A.E., Pei J., Cong Q., Gao X.J. “Orthogonalized human protease control of secreted signals.”
Available on BioRxiv: https://doi.org/10.1101/2024.01.18.576308
Kinney S.M., Ortaleza K., Vlahos A.E., Sefton M.V. “Degradable methacrylic acid-based synthetic hydrogel for subcutaneous islet transplantation.” Biomaterials 281, 121342, 2022.
Mahou R., Vlahos A.E., Shulman A., Sefton M.V. “Interpenetrating alginate-collagen polymer network microspheres for modular tissue engineering.” ACS Biomater. Sci. Eng. 4 (11), 3704- 3712, 2018.
Mahou R., Zhang D.K.Y., Vlahos A.E., Sefton M.V. “Injectable and inherently vascularizing semi-interpenetrating polymer network for delivering cells to the subcutaneous space.” Biomaterials (131), 27-35, 2017.
Ciucurel E.C., Vlahos A.E., Sefton M.V. “Using Del-1 to tip the angiogenic balance in endothelial cells in modular constructs.” Tissue Eng Part A (7-8), 1222-1234, 2014.
Patents
Vlahos A.E., Kang J., Gao X.J. “Protease-controlled secretion and display of intercellular signals.” U.S. Patent Filed No. 17/985,624.
Vlahos A.E., Call C.C., Gao X.J. “Programmable control of intercellular signals using protein-protein interactions.” U.S. Provisional Patent Application No. 63/486,904.